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AJNR Am J Neuroradiol 1995 Jan;16(1):39-48; discussion 49-52 
<b>Preliminary experience with MR-guided thermal ablation of brain tumors. </b>
Anzai Y, Lufkin R, DeSalles A, Hamilton DR, Farahani K, Black KL. 
Department of Radiological Science, University of California, Los Angeles Medical Center 90024-1721. 

PURPOSE: To evaluate the feasibility of a technique of MR-guided stereotactic radio frequency ablation, which was developed as a minimally invasive treatment for brain tumors, ...
METHODS: Fourteen lesions in 12 patients with primary and metastatic brain tumors were treated with this technique and followed for up to 10 months. ...The radio frequency lesion was generated in the awake patient by increasing the temperature to 80 degrees C within the tumor for 1 minute. This was repeated until the entire tumor volume was destroyed. MR imaging was performed before, during, and immediately after the radio frequency procedure, ...
RESULTS: MR imaging clearly showed well-defined radio frequency lesions and provided feedback for treatment planning. ...The sequential MR imaging showed the radio frequency lesions decreased in volume in all cases, suggesting focal control. 
CONCLUSION: <b>Stereotactic MR-guided radio frequency brain tumor ablation is a feasible and promising technique that can be an attractive brain tumor treatment alternative. MR provided not only accurate tumor location but also visualization of feedback of thermal tissue changes that reflected therapeutic effect.</b> 
&&url PMID: 7900601 
