Each person has 46 chromosomes which together store 30,000 genes.&nbsp; Chromosomes can be seen under a microscope when a cell divides.&nbsp; Cytogenetic aberrations are abnormalities that can be seen in the chromosomes. Most leiomyosarcomas have extremely complex cytogenetic aberrations [1,2,3]. One cytogenetic aberrations found in at least 50% of leiomyosarcomas is deletion of the chromosome 1 short arm [2,3] (Chromosomes have a short and long arm). This deletion is not useful diagnostically, because it is also found, albeit less frequently in leiomyomas [4] and in various other soft tissue tumors. 