Tumors that are chemotherapy or radiation sensitive can be cured by these methods.  Some examples are Hodgkin's Lymphoma, and Acute Lymphocytic Leukemia in children.  LMS is not curable by chemotherapy or radiation.  And sarcomas, as a group, are relatively resistant to chemotherapy and radiation, although there is variation within the group.   There is even variation within the group of leiomyosarcoma tumors, as to response to chemotherapy and/or radiation.
 
Surgical resection with clear margins is the gold standard of treatment for Leiomyosarcoma. For LMS, chemotherapy and/or radiation will not bring a cure, but can sometimes bring a remission, or will enable surgical resection.

<b>One considers chemotherapy in the following situations:</b>