Clin Oncol (R Coll Radiol) 1995;7(2):123-6 
<b>Hip complications following chemoradiotherapy.</b> 
Jenkins PJ, Montefiore DJ, Arnott SJ. St Bartholomew's Hospital, London, UK. 
&&url PMID: 7619762 


J Periodontol 1993 Dec;64(12):1253-8 
<b>Severe progressive periodontal destruction due to radiation tissue injury.</b> 
Yusof ZW, Bakri MM. Department of Oral Pathology, Oral Medicine, and Periodontology, Dental Faculty, University of Malaya, Malaysia. 
.... Radiation bone injury is a long-term manifestation which could progress to osteoradionecrosis. ... The possible pathogenesis of these events is described as they relate to the sequential radiographic changes observed over a period of 6 years until the involved teeth were exfoliated. .... 
&&url PMID: 8106955  


Radiat Med 1989 Jan-Feb;7(1):32-5 
<b>Thoracic vertebral photopenia may predict fatty changes of the corresponding bone marrow following irradiation.</b> 
Shih WJ, Li CY, Coffey CW, Maruyama Y. Nuclear Medicine Division, Veterans Administration Medical Center, Lexington, Kentucky. 
.... At autopsy a section of the corresponding bone marrow showed extensive fatty changes with very few residual blood vessels. Radiation damage of the vascular networks may significantly reduce the blood supply, when integrity of the blood supply is essential for delivery of a normal bone image by the bone-imaging agent. Interruption of blood supply may cause photopenia, and this interruption plus irradiation to marrow elements may also affect the hematopoietic activity of the corresponding bone marrow. ... 
&&url PMID: 2762587


Acta Oncol 1988;27(2):117-22 
<b>Spontaneous radiation-induced rib fractures in breast cancer patients treated with postmastectomy irradiation. A clinical radiobiological analysis of the influence of fraction size and dose-response relationships on late bone damage.</b>
Overgaard M. Department of Oncology and Radiotherapy, Radiumstationen, Aarhus, Denmark. 

...<b>Patients treated with a large dose per fraction had significantly higher incidence of late bone damage (19%) than patients treated with a standard dose per fraction (6%)</b> ... 
&&url PMID: 3390342

 
Gan No Rinsho 1987 Aug;33(10):1131-3
<b>[Rib fracture after postoperative tangential irradiation in breast cancer].</b> [Article in Japanese] 
Shimamura Y, Jingu K, Hayabuchi N, Miyoshi M, Masuda K. Dept. of Radiotherapy, National Kyushu Cancer Center. 
Incidence of rib fracture was analyzed for 118 postoperated breast cancer patients who were tangentially irradiated at the Department of Radiology, Kyushu University, from 1961 to 1976 and followed more than 5 years. Rib fracture was observed in 5% and 50% of cases treated with total radiation doses of 32.5 Gy and 52.5 Gy respectively. 
&&url PMID: 3669304 


Oral Surg Oral Med Oral Pathol 1983 Jun;55(6):580-8 
<b>Actinomyces israelii in osteoradionecrosis of the jaws.</b> Histopathologic and immunocytochemical study of five cases. 
Happonen RP, Viander M, Pelliniemi L, Aitasalo K. 
Infections and operation as the precipitant/s of osteo radio necrosis of the jaw.
&&url PMID: 6348637 


Am J Anat 1978 Feb;151(2):295-305 
<b>Effects of therapeutic radiation on microstructure of the human mandible.</b> 
Savostin-Asling I, Silverman S Jr. 
Mandibular bone from eight patients who had received therapeutic radiation (6,000-7,200 rads) for intra-oral cancer was obtained at surgery (1 month to 9 years after radiation) and compared histologically with non-irradiated mandibular bone from five subjects. Measurements made on the internal remodeling process of cortical bone included the extent of internal surface and the fraction indicating resorption, and the proportions of osteones which were incomplete (less than 3/4 filled with matrix), complete, and plugged. Appreciable differences were observed in all parameters except plugged osteones. <b>The findings suggested early cessation of osteogenesis, and somewhat later cessation of resopriton, without subsequent resumption of either process. The histologic appearance of the osteoblasts, osteoclasts, and osteones was in accord. Microfractures found in the irradiated bone were not seen to have healed. Radiation damage to the osteoprogenitor cells is postulated.</b> 
&&url PMID: 626157