
# An aggressive, bone-destructive metastasis of squamous cell carcinoma was injected intratumorally with cisplatin, followed by radiotherapy, for relief of symptoms. [19] 

# An endoscopic intratumoral injection of 5-fluorouracil was given into a gastric cancer primary, along with systemic chemotherapy, which brought about a partial response. [18]

# A case of a gigantic cystic craniopharyngioma was treated with intratumoral injections of bleomycin. The mass had eroded the skull base and extended to the sphenoid bone. A total of eight intratumoral injections through an Ommaya reservoir were given. Six months after treatment, there was complete regression of the lesion and improvement in both visual and endocrinological symptomatology. [24]

# A Merkel cell carcinoma of the mandibular area was treated successfully by direct intratumoral administration of recombinant human tumor necrosis factor. [29]

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