
Dacarbazine is a classic drug used for sarcomas.  It was often part of a cocktail like MAID or CYVADIC.  It is an intravenous drug, which is metabolized in the body to the active agents.  Temozolomide, a new drug, is closely related and is hydrolyzed to the same agents. Temozolomide is an oral agent, however.  DTIC is less expensive than temozolomide.
