Khirurgiia (Mosk) 1999;(10):60-2 
<b>[Clinical features, diagnosis and treatment for trophic, late radiation ulcers and ulcers undergone malignant transformation].</b> [Article in Russian] 
Tostykh PI, Stranadko EF, Koraboev UM, Duvanskii VA, Kalinin MR, Vatlin KI. 
Clinical and histological examinations of 1562 patients with trophic and advanced radiation ulcers were carried out during 30 years. Malignant transformation of the ulcers has been revealed in 14 of them: sarcoma--in 1, and cancer--in 13. From all the patients with advanced radiation ulcers, malignant transformation was detected in 7.07%, and in cases of ulcers of the other genesis--in 0.81% of cases. Malignant transformation of ulcers of non-radiation genesis occurs on the average after 19 years, and of radiation one--after 3.8 years. Early diagnosis of skin cancer, at the site of the ulcer is rather difficult and depends thoroughly on oncological alert and timely morphological examination of various skin areas. A new, rather perspective and relatively simple method of treatment for ulcerative forms of cancer of the skin is <b>photodynamic therapy (PhDT).</b> This method showed to be effective even in those patients who failed conventional methods of treatment (relapses), or had contraindications. PhDT has broaden the armory of the oncologists and oncodermatologists for treatment of complicated forms of cancer of the skin. 
&&url PMID: 10540557 


Klin Monatsbl Augenheilkd 1999 Dec;215(6):355-60 
<b>[Long-term radiation damage to the skin and eye after combined beta- and gamma- radiation exposure during the reactor accident in Chernobyl].</b> [Article in German]  Junk AK, Egner P, Gottloeber P, Peter RU, Stefani FH, Kellerer AM. Ludwig-Maximilians-Universitat Munchen, Augenklinik. akj19@columbia.edu 
&&url PMID: 10637800  


Biol Trace Elem Res 1998 Jul;63(1):11-8 
<b>Structural and trace element changes in scalp hair of radiographers.</b> 
Man AC, Zheng YH, Mak PK. Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Kowloon. 

...<b>The structural damage to the hair follicles of the radiographers was quite obvious, and this may be a good qualitative indicator of radiation damage at low doses.</b> The concentrations of aluminum (Al), potassium (K), and vanadium (V) in hair of the radiographers were significantly higher, whereas those of antimony (Sb) and magnesium (Mg) were significantly lower than those of nonradiographers. Some of our findings were quite consistent with those of others in determining the changes in trace element concentrations in irradiated tissue. 
&&url PMID: 9764566 


Radiother Oncol 1996 Jul;40(1):23-30 Comment in: Radiother Oncol. 1996 Jul;40(1):1-3 Radiother Oncol. 1997 Jun;43(3):324-5 
<b>Underprediction of human skin erythema at low doses per fraction by the linear quadratic model.</b> 
Hamilton CS, Denham JW, O'Brien M, Ostwald P, Kron T, Wright S, Drr W. Radiation Oncology Department, Newcastle Mater Misericordiae Hospital, NSW, Australia. 
&&url PMID: 8844884 


Hautarzt 1995 May;46(5):319-24 
<b>[In vitro and in vivo studies of local disinfection and wound healing].</b> [Article in German] 
Hagedorn M, Hauptmann S, Essinger U, Kaden P, Mittermayer C. Hautklinik der Stadtischen Kliniken, Darmstadt. 
Wound healing represents a dynamic process of increasing scientific interest, ...<b>Additionally it was shown, using cultures of fibroblasts, that chiniofon-containing antiseptic does not inhibit the growth of fibroblasts, whereas PVP-iodine solution, a widely used antiseptic, clearly reduces the growth of fibroblasts. The good clinical results in the treatment of acute and chronic radiation damage indicate that chiniofon-containing antiseptic may have antiflammatory activity.</b> 
&&url PMID: 7607895


Plast Reconstr Surg 1993 Aug;92(2):294-300 
<b>Surgical treatment of radiation injuries of the hand.</b>
Milanov NO, Shilov BL, Tjulenev AV. Department of Microsurgery, National Research Center of Surgery, Academy of Medical Sciences, Moscow, Russia. 
This paper describes the wound management and treatment of 12 consecutive patients with severe radiation damage to the hands. Three of these were secondary to therapeutic radiation ...and nine were healthy professional people exposed to radiation in the work-place. All lesions were characteristic radiation burns with ulcerative necrotic changes of the skin and subcutaneous tissues...We conclude that management of radiation-induced injuries to the hand should be done with aggressive debridement and immediate coverage with well-vascularized flaps, either regional or free-tissue transfers. This will result in adequate wound healing and the most rapid, effective return of function with rapid institution of therapeutic modalities. 
&&url PMID: 8337280 


J Am Acad Dermatol 1984 Jul;11(1):53-7 
<b>Drug eruptions presenting at sites of prior radiation damage (sunlight and electron beam).</b> 
Shelley WB, Shelley ED, Campbell AC, Weigensberg IJ. 
Two patients are described in whom sunburn and electron beam radiodermatitis, respectively, were critical determinants in localizing the initial presentation of drug eruptions. In the first instance, a severe sunburn of the back and thighs was followed 7 months later by the appearance of a toxic epidermal necrolysis drug reaction to trimethoprim-sulfamethoxazole in the exact sites of the previous bullous sunburn reaction. In the second patient, a radiodermatitis of the left upper arm due to electron beam therapy for metastatic breast cancer was followed 7 weeks later by a codeine drug reaction confined to the area of the radiodermatitis. In both instances, oral rechallenge with the offending drug reproduced the eruption. 
&&url PMID: 6234333


J Dermatol Surg Oncol 1984 Mar;10(3):200-3 
<b>Radiation-induced basal-cell carcinoma.</b> 
Allison JR Jr. 
Four patients developed 129 basal-cell carcinoma (BCC) in areas of prior radiation without evidence of radiation damage. The time lag between radiation and appearance of the cancers was 20 years. It is proposed that we are dealing with a subset of the population not previously recognized. These patients were not related to other groups, such as the nevoid basal-cell carcinoma syndrome. 
&&url PMID: 6699258 


Ann Dermatol Venereol 1979 Nov;106(11):875-82 
<b>[On five new cases of association of basal cell carcinoma and multiple Pinkus fibroepithelial tumors on the spine following radiation damage to the skin (author's transl)].</b> [Article in French] Colomb D, Brechard JL, Gho A, Caux Y. 
The authors report five new cases associating basal cell epithelioma and multiple Pinkus fibro-epithelial tumors on the spine after radiation damage to the skin. One of them had previously published three similar observations: so his experience refers to eight cases. The authors recall similar cases of the literature, they discuss the relations between basal cell epitheliomas and Pinkus premalignant fibro-epithelial tumors of the skin. Histologically they saw several aspects of transition between the two types of tumors. They study the patterns of cancers found after radiation therapy, influence of type of radiations, dose, age, and intervals since X-rays. <b>As regards such cases, the necessity of systematically searching for previous radiations by X-rays in the affected zone is emphasized.</b> 
&&url PMID: 539699