<b>Discussion of Factors Affecting Chemosensitivity/Resistance Testing of LMS tumors</b>

There are two terms you will need to know. In vitro [in VEE troe] means ''in glass'', which means in the laboratory test tubes; in this case how chemo agents act upon the cultures of the tumor cells. In vivo [in VEE voe] means ''in the living''. It means how the chemo agent performs ''clinically''; how it reacts upon the tumor when in the patient's body. Ex vivo means in vitro.

<b>Chemosensitivity Testing: </b>
How a chemotherapy agent performs in test tubes may be very different from the performance inside a body. Because there are many factors which happen in tumors and bodies which are not applicable to studying in a tissue culture: 