
Dr. Berwick of MSKCC [Memorial Sloan Kettering Cancer Center] conducted a study of LMS patients a few years ago.  Subjects submitted a swab of their saliva, and a separate swab from a spouse or other biologically unrelated person.

She found that LMS patients had more fragile/breakable DNA.

She also found, in an earlier study, that
"Patients with soft tissue sarcoma were 5.7 times more likely to be mutagen sensitive than controls (P = 0.01), as determined after dividing subjects into sensitive or not sensitive groups based on the median b/c among controls. As mutagen sensitivity has been shown to be associated with a number of cancers and appears to reflect genetic susceptibility, this assay may be an appropriate biomarker for radiation sensitivity or it may be a marker of susceptibility to soft tissue sarcoma."
&&url PMID: 11746758
